Ringing the changes

Ringing the changes

JCS in 2010 - ringing in the changes.

Calcium signalling: Ringing changes to the ‘bell-shaped curve’

The stimulation of cells with agonists that activate phospholipase C, and hence increase the cytoplasmic concentration of inositol 1,4,5-trisphosphate (IP3), often produces complex intracellular Ca2+ signals, such as Ca2+ waves [1]. The key to understanding how Ca2+ waves propagate was the observation that the Ca2+ wave velocity and concentration gradient was maintained as the Ca2+ waves swept ...

The emergence of ringing vertigo.

Ding dongmerrily on high, goes the famous Christmas carol, but for some of the United Kingdom’s 40 000 campanologists the bells have not been ringing so merrily. Instead, church bell ringers have this year been complaining of a disorder that has been forcing them to abandon their towers and steeples and seek out hypnotherapists and counsellors in search of a cure. Symptoms include vertigo, a se...

The Ringing of Euler’s Disk

The motion of disks spun on tables has the well-known feature that the associated acoustic signal increases in frequency as the motion tends towards its abrupt halt. Recently, a commercial toy, known as Euler’s disk, was designed to maximize the time before this abrupt ending. In this paper, we present and simulate a rigid body model for Euler’s disk. Based on the nature of the contact force be...